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Etiology and Pathogenesis of Recurrent Aphthous Stomatitis

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¼­ºÀÁ÷, ÀÌ°æÀº,
¼Ò¼Ó »ó¼¼Á¤º¸
¼­ºÀÁ÷ ( Suh Bong-Jik ) - ÀüºÏ´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
ÀÌ°æÀº ( Lee Gyeong-Eun ) - ÀüºÏ´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°­³»°úÇб³½Ç

Abstract

Àç¹ß¼º ¾ÆÇÁŸ¼º ±Ë¾çÀº ÈçÈ÷ ¹ß»ýÇÏ´Â ºñƯÀÌÀû ±¸°­Á¡¸·ÁúȯÀÌ´Ù. ±Ë¾çÀº ºñ°¢È­ Á¡¸·¿¡ ¹ß»ýÇÏ°í ÀÏÁ¤½Ã°£ÀÌ È帥 ÈÄ Ä¡À¯°¡ µÇÁö¸¸, ½ÉÇÑ ÅëÁõÀ¸·Î ÀúÀÛ°ú ´ëÈ­ µîÀÇ ÀÏ»óÈ°µ¿¿¡ Å« ÁöÀåÀ» ÃÊ·¡ÇÑ´Ù. ±×·¯³ª ¾ÆÁ÷±îÁö Á¤È®ÇÑ ¿øÀΰú ±âÀüÀÌ ¹àÇôÁöÁö ¾Ê¾Æ Ưº°ÇÑ Ä¡·á¹æ¹ýÀÌ ¾ø¾î¼­ ´ëÁõÀûÀÎ ¹æ¹ýÀ¸·Î Ä¡·á°¡ ÀÌ·ç¾îÁø´Ù. ÀÌ¿¡ ÀúÀÚ´Â ¾ÆÇÁŸ¼º ±Ë¾çÀÇ ¿øÀΰú ±âÀü¿¡ ´ëÇÑ ¹®ÇåÀ» °íÂûÇÏ¿© ÃֽŰ³³äÀ» ÆľÇÇÏ°í ÇâÈÄ ³ª¾Æ°¡¾ß ÇÒ ¿¬±¸¹æÇâÀ» »ý°¢ÇØ º¸°íÀÚ ÇÑ´Ù.

Recurrent aphthous stomatitis is common oral disease in the world. It is characterized by multiple, recurrent, painful ulcer with circumscribed margins, erythematous haloes and yellow or grey floors. Patients with recurrent aphthous stomatitis suffer from its painful ulcer. But unfortunately, its etiology and pathogenesis is not clear and still unknown. So we review etiology and pathogenesis of recurrent aphthous ulcer and wish to propose direction of the future study.

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Àç¹ß¼º ¾ÆÇÁŸ¼º ±Ë¾çÀÇ ¿øÀÎ;Àç¹ß¼º ¾ÆÇÁŸ¼º ±Ë¾çÀÇ º´¸®±âÀü;T-cell ¸é¿ª¹ÝÀÀ
Heat shock protein;Recurrent aphthous stomatitis;Etiology;Pathogenesis;T-cell cytotoxicity

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